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What Is Roxicodone?
This medication may also be used for other purposes as determined by your doctor. Because it can interact with various drugs and medical conditions, it is critical to inform your doctor or pharmacist of all prescription, over-the-counter, or herbal supplements you are taking.
Important Safety Information
Do not take Roxicodone if you are currently using sodium oxybate or if you have taken a monoamine oxidase inhibitor (MAOI) such as phenelzine within the last 14 days. Some medications can interact with Roxicodone and may require careful dosage adjustment or additional monitoring. These include:
Barbiturates (e.g., phenobarbital)
Cimetidine
Mixed agonist/antagonist opioids (e.g., pentazocine)
Naltrexone
Phenothiazines (e.g., chlorpromazine)
Rifampin
Never start or stop any medication without consulting your healthcare provider.
Medical Conditions to Disclose
Let your doctor know if you have any of the following:
Liver, kidney, or gallbladder issues
Gastrointestinal conditions such as inflammation or bowel obstruction
History of surgery, especially involving the digestive tract
Breathing disorders such as asthma, COPD, or emphysema
Heart conditions, low blood pressure, or blood disorders like porphyria
Prostate problems, thyroid dysfunction, or adrenal gland issues like Addison’s disease
Seizure disorders or head injuries
Mental health conditions or a history of substance use or alcohol abuse
This medication is not appropriate for everyone and may be dangerous in patients with certain medical histories.
When Not to Take Roxicodone
Do not take Roxicodone if:
You are experiencing an active asthma attack
You suffer from severe respiratory problems, including chronic obstructive pulmonary disease (COPD)
You have a recent brain injury or conditions causing increased pressure in the skull
You are severely drowsy or intoxicated
You have untreated diarrhea caused by infection or antibiotics
Use Only As Directed
Always follow your doctor’s instructions when taking Roxicodone. Taking more than prescribed, or using it for longer than directed, can lead to dependence, overdose, or life-threatening side effects.
If you have any concerns or experience unusual symptoms while using this medication, contact your healthcare provider immediately.